San Francisco Vacation Packages

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Your San Francisco Vacation

When a fun city break is calling, answer it with a vacation package to San Francisco. The neighborhood of El Cangrejo, which is good for distilleries and craft breweries, bars and pubs and cafes, makes a fantastic base for your adventures. You'll want to do a little exploring during your trip to San Francisco. Carve out some time for top attractions such as Miraflores Locks, Bridge of the Americas and Metropolitan Cathedral of Panama. That dream San Francisco vacation is just a few clicks away. Explore flights, accommodations and more on Expedia for an adventure that's tailored to suit your travel style.

Top Holiday Package Deals in San Francisco

Price found within the past 48 hours. Click for updated prices.
Villa Marina Hotel

Villa Marina Hotel

3.5 out of 5
Price was CA $2,493, price is now CA $1,813 per person
CA $1,813
per person
Jun 28 - Jul 5
found 17 hours ago
Roundtrip non-stop flight included
Toronto (YYZ) to Panama City (PTY)
9/10 Wonderful! (154 reviews)
The Villa Marina Hotel is an older property with only nine rooms. Overall the property is nice and well maintained. With the price they can’t invest a great amount in the infrastructure and stay in business. The grass area would benefit from expansion, this would reduce mud; between mud and black sand the room and patio get a bit dirty. Also a stone or brick base near the outside shower would be good. In a perfect world, bricks to the beach. The rocks are sharp. The food menu is somewhat limited, but that seems true in the entire town. Difficult to find Gluten Free. The food quality is good. Prices are about average. The drink menu is extensive and prices are good. Pros: Room is well equipped Housekeeping is very good On the beach Short walk along beach to town Beautiful sunsets Swimming pool is nice Staff are helpful and very friendly A new poolside bar is coming The grocery store in town is wonderful. Cons: The music on weekends and some other days from dusk until 04:00 AM is unacceptable. This is nearly a km up the beach and it is still loud and doesn’t allow for good sleep. A great deal of development is occurring. The little surf town will likely see some big changes. Potentially Stingrays and Sea-snakes in area. Saw a couple of sea snakes on beach. Shuffle when walking in water is recommended. Did not hear of any bites or stings. At least 30 minutes to nearest hospital, although, I understand there are some trained locals in medical aid and an AED.

Reviewed on Apr 25, 2026

Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4 out of 5
Casco Viejo
Price was CA $4,832, price is now CA $2,915 per person
CA $2,915
per person
Jul 8 - Jul 15
found 6 hours ago
Roundtrip non-stop flight included
Edmonton (YEG) to Panama City (PTY)
9.2/10 Wonderful! (1,009 reviews)
The perfect place to stay and enjoy Casco Viejo. Right on the plaza so there is a lot of activity at night. The Panama Canal museum is adjacent and very interesting to see before you to visit the canal.

Reviewed on Apr 25, 2026

Casa Mallet by Wynwood House

Casa Mallet by Wynwood House

4 out of 5
Casco Viejo
Price was CA $3,913, price is now CA $2,846 per person
CA $2,846
per person
Jul 8 - Jul 15
found 7 hours ago
Roundtrip non-stop flight included
Edmonton (YEG) to Panama City (PTY)
9.8/10 Exceptional! (27 reviews)
In the middle of the old town, lovely rooftop. Beautiful apartment. Easy check in. WhatsApp line is available if anything was needed or if we had questions.

Reviewed on Mar 12, 2026

Ciel y Miel

Ciel y Miel

3 out of 5
Price was CA $3,986, price is now CA $2,908 per person
CA $2,908
per person
Jun 28 - Jul 5
found 17 hours ago
Roundtrip non-stop flight included
Toronto (YYZ) to Panama City (PTY)
10/10 Exceptional! (10 reviews)
The views from this mountain-top boutique hotel are extraordinary.

Reviewed on Feb 1, 2026

Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 out of 5
San Francisco
Price was CA $2,812, price is now CA $2,078 per person
CA $2,078
per person
Jul 8 - Jul 15
found 6 hours ago
Roundtrip non-stop flight included
Edmonton (YEG) to Panama City (PTY)
8.4/10 Very Good! (1,505 reviews)
Clean and convenient

Reviewed on Apr 21, 2026

Where to stay in San Francisco

Find the best San Francisco areas and neighborhoods for the activities you enjoy most. Learn more about San Francisco
View of the Panama City Old Town

Casco Viejo

Unique features of Casco Viejo include the historic sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area.

Find hotels in Casco Viejo

San Francisco Hotel Deals

Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel

3.5 out of 5
Italy Avenue, Punta Paitilla Panama City Panama
Fully refundableReserve now, pay when you stay
The price is CA $141 per night from May 8 to May 9
CA $141
CA $155 total
May 8 - May 9
includes taxes & fees
9.4/10 Exceptional! (2,140 reviews)
Breakfast, clean, staff, location

Reviewed on Apr 26, 2026

Plaza Paitilla Inn Hotel
Courtyard by Marriott Panama Multiplaza Mall

Courtyard by Marriott Panama Multiplaza Mall

4 out of 5
Via Israel Multiplaza Pacific Mall Panama City Panama
The price is CA $161 per night from May 11 to May 12
CA $161
CA $178 total
May 11 - May 12
includes taxes & fees
9/10 Wonderful! (1,007 reviews)
El hotel tiene excelente ubicación, creo que pudieran remodelar los ascensores y otras áreas, el personal es muy amable y atento.

Reviewed on Apr 24, 2026

Courtyard by Marriott Panama Multiplaza Mall
JW Marriott Panama

JW Marriott Panama

5 out of 5
Calle Punta Colon, Punta Pacifica Panama City Panama
Fully refundableReserve now, pay when you stay
The price is CA $371 per night from May 15 to May 16
CA $371
CA $408 total
May 15 - May 16
includes taxes & fees
9/10 Wonderful! (1,003 reviews)
Very good. 5star

Reviewed on Apr 26, 2026

JW Marriott Panama
See all 1,548 properties in San Francisco
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Vacations
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Frequently asked questions

How much does a San Francisco vacation package cost?
Much less than you might think — from a low CA $1,813, in fact! By bundling hotels, flights and car rentals into a custom-built vacation package, your San Francisco escape is only clicks away.
How do I get a cheap travel package to San Francisco?
Lock in flights that suit your schedule, add a hotel to your booking and watch how much you save with a San Francisco vacation package. It's that easy! From flights and hotels to rental cars and activities, Expedia makes traveling on the cheap easy. And with more than 550 partner airlines and 1,000,000 hotel options around the globe to pick from, you'll never be short of choice.
Where should I stay in San Francisco?
Make sightseeing easy by staying near San Francisco's main attractions. Miraflores Locks and Metropolitan Cathedral of Panama are two which top many visitors' bucket lists.
What are the top hotels in San Francisco?
If this will be your first visit to San Francisco, secure a room at Sublime Apartment City Center. Ph Boutique Quartier Atlapa or New Cozy Apartment Ocean View. Quartier Del Mar. Both hotels will make you feel at home and are popular options with lots of travelers.
How far in advance should I book my San Francisco vacation?
It can be hard to know when is the ideal time to book your trip to San Francisco. But typically the earlier you book, the lower the prices. Sometimes, you can reserve your flights and hotels up to a year prior to your departure date. If you're eager to escape on a last-minute getaway, no need to fret! There are unbeatable deals announced on Expedia every day.
What does an Expedia San Francisco travel package include?
That mostly depends on you. You can choose from a range of San Francisco packages, such as a hotel, rental car and flight. You can also book a hotel and a flight, or a flight and a rental car. Once you've made your booking, you can add the fun stuff like experiences and tours. Whatever your ideal San Francisco vacation looks like, you're sure to save!
What should I know before booking a San Francisco travel package?
So many places to go, so many things to see and do. With a travel package, you'll be able to afford more of them. Bundle your hotels, flights and rental cars and land big savings.
Can I choose my airline with a San Francisco Expedia vacation package?
Yes, definitely. Expedia has more than 550 airline partners to choose from worldwide. With such a huge range of choice, finding the ideal carrier to whisk you off to San Francisco won't be difficult.
If I'm not able to travel, can I cancel my San Francisco vacation package?
Your situation can change in a flash, so yes, you can. You may be able to amend or cancel your San Francisco vacation package for free if you've booked in the last 24 hours. For older bookings, you can still make changes, but your car rental company, airline or hotel may charge a fee. Need more information? Look up our Customer Service Portal. We'll help make sure your trip goes off without a hitch.

Discover the most popular places to visit in San Francisco

Multiplaza Pacific Mall

Multiplaza Pacific Mall

During your trip to Panama City, you can enjoy retail therapy at Multiplaza Pacific Mall. You can enjoy the restaurants while in the area.

Multiplaza Pacific Mall

Omar Torrijos Recreational Park

Omar Torrijos Recreational Park is just one of the places to see in Panama City, so why not enjoy the other things to explore during your travels? Amble around this vibrant area's seaside and enjoy its lively bars.

Omar Torrijos Recreational Park

Things to do

Panama Canal Half Transit Experience

Panama Canal Partial Transit

CA $207
per adult
86% of travellers recommend
Panama Canal Partial Transit
The OG Crawl by The Panama Barcrawl -

The OG Crawl by The Panama Barcrawl - (Panama City, Panama)

CA $90
per adult
98% of travellers recommend
The OG Crawl by The Panama Barcrawl - (Panama City, Panama)
Panama City Visit an Indian town Embera and waterfall with lunch

Panama City Visit an Indian town Embera and waterfall with lunch

CA $67
per adult
96% of travellers recommend
Panama City Visit an Indian town Embera and waterfall with lunch
See all activities in Panama City
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.